Florid retinopathy: a rapidly progressive form of proliferative diabetic retinopathy

Florid Diabetic Retinopathy in a Young Patient

In May 2008, a 21-year-old single, non-obese, diabetic lady was referred to our clinic for routine eye examinations. The patient had been diagnosed with diabetes mellitus three months earlier and was receiving 100 milligrams of metformin daily and 80 milligrams of gliclazide twice daily orally, consistently maintaining her blood glucose levels between 72-90 mg/dl. She had a positive family hist...

Proliferative diabetic retinopathy.

Heritability of Proliferative Diabetic Retinopathy

OBJECTIVE Diabetic nephropathy clusters in families, suggesting that genetic factors play a role in its pathogenesis. We investigated whether similar clustering exists for proliferative retinopathy in families with two or more siblings with type 1 diabetes. RESEARCH DESIGN AND METHODS The FinnDiane Study has characterized 20% (4,800 patients) of adults with type 1 diabetes in Finland. In 188 ...

Association of CXCL12 and CXCR4 Genes Polymorphism with Proliferative Diabetic Retinopathy in Diabetic Patients

Introduction: Patients with diabetes are prone to develop complications related to the retina. So far, several genes have been reported in connection with the progression of retinopathy, and a group of these genes is genes involved in angiogenesis. CXCL12 and CXCR4 genes are among the most important genes in this path, which have been less studied and investigated. The aim of this study was to ...

Predicting Development of Proliferative Diabetic Retinopathy

OBJECTIVE Identifying individuals most at risk for diabetic retinopathy progression and intervening early can limit vision loss and reduce the costs associated with managing more advanced disease. The purpose of this study was to identify factors associated with progression from nonproliferative diabetic retinopathy (NPDR) to proliferative diabetic retinopathy (PDR). RESEARCH DESIGN AND METHO...